Recombinant Murine FGF-4 0 ReviewsSubmit a Review Product Details Catalog Number: 450-57 Description: FGF-4 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant Murine FGF-4 is a 19.0 kDa protein consisting of 173 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-4 AA Sequence: APNGTRHAEL GHGWDGLVAR SLARLPVAAQ PPQAAVRSGA GDYLLGLKRL RRLYCNVGIG FHLQVLPDGR IGGVHADTRD SLLELSPVQR GVVSIFGVAS RFFVAMSSRG KLFGVPFFTD ECKFKEILLP NNYNAYESYA YPGMFMALSK NGRTKKGNRV SPTMKVTHFL PRL Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 0.4-1.0 ng/ml. Calculated Molecular Weight: 19 kDa Accession Number: Q03142 Gene ID: 14175 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. Cross Reactivity Cited in References: Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Recent Citations First Author Mak, K H Title Histone demethylase JMJD2B/KDM4B regulates transcriptional program via distintive epigenetic targets and protein interactors for the maintenance of trophoblast stem cells Citation Scientific Reports; 11(1) pg884 PubMed ID 33441614
