Growth Factors & Cytokines

Recombinant Murine IL-15

Product Details

Catalogue Number: 210-15

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.  IL-15 exerts its biological activities primarily on T cells.  It is also essential in the development, survival and activation of NK cells.  Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I.  Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.  Recombinant Murine IL-15 is a 13.3 kDa protein consisting of 115 amino acid residues.

Source: E.coli

Synonyms: IL-T


Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by the stimulation of the proliferation of murine CTLL-2 cells is ≤ 5.0 ng/ml, corresponding to a specific activity of ≥ 2 x 105 units/mg.

Calculated Molecular Weight: 13.3 kDa

Accession Number: P48346

Gene ID: 16168


1mg will be provided as 2x500μg.

Country Of Origin: USA

Not for human use.

Country Of Origin: USA

Not for human use.


Existing reviews
Product with great consistency
We have been using this cytokine for splenic NK cells in numerous publications for the past 5 years. Great consistency!
From:  Jin | Date:  21/07/2020
Works Like Magic
Have been using this cytokine for past 1year and has worked everytime. Very helpful for stimulating and expanding T cell population. Does a great job while performing in-vivo T cell transfer experiments.
From:  Vineet | Date:  10/08/2020
Consistently great cytokine to keep mouse T cells happy
We routinely use this pro-survival homeostasis cytokine to generate mouse memory CD8+ T cells. The pricing and consistency of this cytokine can't be beat, and we have been using it for almost 20 years. All of our cytokines using in our lab are from peprotech.
From:  Chirag | Date:  31/08/2020
Works very well to generate CD8 memory T cells
We have been using this cytokine for the last 5 years to generate CD8 memory T cells. It consistently provided very good differentiation profile in terms of surface marker expression, cytokine production and metabolic features.
From:  mauro | Date:  19/08/2021