Recombinant Murine IL-17E 0 ReviewsSubmit a Review Product Details Catalogue Number: 210-17E Description: IL‐17E is a disulfide‐linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL‐17 family of structurally‐related cytokines that share a highly conserved C‐terminal region, but differ from one another in their N‐terminal regions and in their distinct biological roles. The six known members of this family, IL‐17A through IL‐17F, are secreted as homodimers. IL‐17E stimulates secretion of IL‐8, and induces activation of the transcription factor NF‐κB in cells that express the IL‐17BR receptor. Recombinant Murine IL‐17E is a 35.0 kDa disulfide‐linked homodimer of two 152-amino-acid polypeptide chains. Source: E.coli Synonyms: Interleukin-17E AA Sequence (monomer): MLRIQEGCSH LPSCCPSKEQ EPPEEWLKWS SASVSPPEPL SHTHHAESCR ASKDGPLNSR AISPWSYELD RDLNRVPQDL YHARCLCPHC VSLQTGSHMD PLGNSVPLYH NQTVFYRRPC HGEEGTHRRY CLERRLYRVS LACVCVRPRV MA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Measured by its ability to induce GROα (CXCL1) secretion in HT‑29 human colon adenocarcinoma cells. Calculated Molecular Weight: 35.0 kDa Accession Number: Reviewed Data Unavailable Gene ID: 140806 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Cancer Immune System Inflammation product.subtitle.recentcitations First Author Liu, C Title Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells Citation Cell Research; 31(10) pg1106-1122 PubMed Id 34239074
