Recombinant Murine KC (CXCL1) 0 ReviewsSubmit a Review Product Details Catalog Number: 250-11 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), CINC (rat) AA Sequence: APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P12850 Gene ID: 14825 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. Cross Reactivity Cited in References: Human, Mouse, Mouse + Bacteria, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing Recent Citations First Author Chang, C W Title Gα13 Mediates Transendothelial Migration of Neutrophils by Promoting Integrin-Dependent Motility without Affecting Directionality. Citation Journal of immunology (Baltimore, Md. : 1950); 207(12) pg3038-3049 PubMed ID 34799423 First Author Yoon, Y Title Activation of the adipocyte CREB/CRTC pathway in obesity. Citation Communications Biology; 4(1) pg1214 PubMed ID 34686752 First Author Lindzen, M Title Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53 Citation Oncogene; 40(21) pg3665-3679 PubMed ID 33941851
