Recombinant Murine MIG (CXCL9)

Product Details

Catalogue Number: 250-18

Description:

MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant Murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: Monokine Induced by Interferon-gamma, CXCL9

AA Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 50.0-150.0 ng/ml.

Calculated Molecular Weight: 12.2 kDa

Accession Number: P18340

Gene ID: 17329

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:

Bacteria, Human, Monkey, Mouse,

Country Of Origin: USA

Not for human use.

Research Interest

COVID-19

Angiogenesis/Cardiovascular

product.subtitle.recentcitations

First Author

Pein, M

Title

Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs

Citation

Nature Communications; 11(1) pg1494

PubMed Id

32198421

First Author

Joutoku, Z

Title

CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.

Citation

Stem Cell Reports; 9(1) pg5165

PubMed Id

30914733

First Author

Xu, Y

Title

Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.

Citation

Nature Communications; 9(1) pg914

PubMed Id

29500416

Chemokines