Recombinant Rat EGF 0 ReviewsSubmit a Review Product Details Catalog Number: 400-25 Description: EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Rat EGF is a 6.2 kDa globular protein containing 54 amino acid residues, including 3 intramolecular disulfide bonds. Source: E.coli Synonyms: Epidermal Growth Factor, Urogastrone, URG AA Sequence: MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Calculated Molecular Weight: 6.2 kDa Accession Number: P07522 Gene ID: 25313 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Cancer Cell Culture Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation Recent Citations First Author Zeng, J Title Autophagy Is Required for Hepatic Differentiation of Hepatic Progenitor Cells via Wnt Signaling Pathway. Citation BioMed research international; 2021 pg6627506 PubMed ID 33928152 First Author Park, G W Title Topical cell-free conditioned media harvested from adipose tissue-derived stem cells promote recovery from corneal epithelial defects caused by chemical burns. Citation Scientific Reports; 10(1) pg12448 PubMed ID 32709896 First Author Qian, Y Title Transplantation of Nurr1-overexpressing neural stem cells and microglia for treating parkinsonian rats. Citation CNS Neuroscience and Therapeutics; 26(1) pg55-65 PubMed ID 31087449
