Recombinant Rat GRO-β/MIP-2 (CXCL2) 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-11 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, Macrophage Inflammatory Protein-2, MIP-2α, GRO2 AA Sequence: VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: P30348 Gene ID: 114105 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Abu-Taha, M Title Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan. Citation Journal of immunology (Baltimore, Md. : 1950); 183(2) pg1393-402 PubMed Id 19553526 First Author Mateo, T Title A critical role for TNFalpha in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles. Citation Blood; 110(6) pg1895-902 PubMed Id 17595330 First Author Burdon, P C Title The CXC chemokine MIP-2 stimulates neutrophil mobilization from the rat bone marrow in a CD49d-dependent manner. Citation Blood; 105(6) pg2543-8 PubMed Id 15542579
