Pre-Coated ELISA Kits

Biogems

Human CD40 Ligand Pre-Coated ELISA Kit

Produktdetails

Katalognummer: BGK29965
Beschreibung:

CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anCHOred CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to ""immunodeficiency with hyper-IgM"", a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. The BioGems Human CD40 Ligand Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure CD40 Ligand with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for CD40 Ligand. It contains E.coli-expressed recombinant CD40 Ligand. The detection antibody is a biotinylated goat polyclonal antibody specific for CD40 Ligand. The kit is analytically validated with ready to use reagents.

Sandwich ELISA:

Assay Type:
Solid Phase Sandwich ELISA: 96-Well Strip Plate
Sensitivity:
<15 pg/ml 
Range:
62.5pg/ml-4000pg/ml
Specificity:
Natural and recombinant Human CD40 Ligand
Uniprot:
  P29965
Interference:
No detectable cross-reactivity with other relevant proteins

Note:

Product supplied by Biogems

Country Of Origin: USA

Not for human use.