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趋化因子

Recombinant Human BCA-1 (CXCL13)

产品详情

产品编号: 300-47
产品描述:
Recombinant Human BCA-1 (CXCL13)

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3 kDa protein containing 87 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand

AA Sequence: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human B cells using a concentration range of 1.0-10.0 ng/ml.

Recombinant Human BCA-1 (CXCL13) Biological Activity Graph

Calculated Molecular Weight: 10.3 kDa

Accession Number: O43927

Gene ID: 10563

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Seda, V
标题
FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.
文献引用
Blood; 138(9) pg758-772
PubMed Id
第一作者
Gimenez, N
标题
Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia
文献引用
Scientific Reports; 10(1) pg22153
PubMed Id
第一作者
Yasuoka, H
标题
Increased both PD-L1 and PD-L2 expressions on monocytes of patients with hepatocellular carcinoma was associated with a poor prognosis
文献引用
Scientific Reports; 10(1) pg10377
PubMed Id

product.subtitle.productreviews

现有评论
For migration assay
We have been using this chemokine to test the ability of our cells to migrate and we always get really good results when working with PBMCs. Highly recommended.
来自:  Jhomary | 日期:  2020/8/26