Animal-Free Recombinant Human CNTF 0 评论Submit a Review 产品详情 产品编号: AF-450-13 产品描述: CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types, including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant Human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Ciliary Neurotrophic Factor AA Sequence: AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTQSYVKH QGLNKNINLD SADGMPVAST DQWSQLTQAQ RLQQNLQAYR TFHVLLARLL QDQQVHFTPT QGDFHQAIHT LLLQVAAFAY QIQQLMILLQ YKIPRNQADG MPINVGDGGL FQKKLWGLKV LQQLSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 50-150 ng/ml. Calculated Molecular Weight: 22.8 kDa Accession Number: P26441 Gene ID: 1270 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Monkey References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 细胞凋亡 骨/骨骼系统/软骨 糖尿病/体重调节 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Yun, Y 标题 CRISPR-mediated Gene Correction Links the ATP7A M1311V Mutations With Amyotrophic Lateral Sclerosis Pathogenesis in One Individual 文献引用 Communications Biology; 3(1) pg33 PubMed Id 31959876 第一作者 Peng, Y 标题 Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina. 文献引用 Cell; 176(5) pg1222-1237.e22 PubMed Id 30712875