Recombinant Human ENA-78 (CXCL5) (5-78 a.a.) 0 评论Submit a Review 产品详情 产品编号： 300-22 产品描述： ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokines that bind to the CXCR1 and CXCR2 receptors. Recombinant Human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues. Source: E.coli Synonyms: Epithelial Neutrophil Activating Peptide-78, CXCL5 AA Sequence: AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKEN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0-10.0 ng/ml. Calculated Molecular Weight: 8 kDa Accession Number: P42830 Gene ID: 6374 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Hamster, Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 化学趋化 免疫系统 炎症 创伤修复 product.subtitle.recentcitations 第一作者 Du, Y 标题 Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. 文献引用 The Journal of Experimental Medicine; 219(7) PubMed Id 35640018 第一作者 Li, Q 标题 mRNA-engineered mesenchymal stromal cells expressing CXCR2 enhances cell migration and improves recovery in IBD. 文献引用 Molecular therapy. Nucleic acids; 26 pg222-236 PubMed Id 34513306 第一作者 Fonseca, K L 标题 Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils 文献引用 Mucosal Immunology; 13(5) pg836-848 PubMed Id 32203062
