Recombinant Human Eotaxin (CCL11) 1 评论Submit a Review 产品详情 产品编号： 300-21 产品描述： Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL11 AA Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0 ng/ml. Calculated Molecular Weight: 8.3 kDa Accession Number: P51671 Gene ID: 6356 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Guinea Pig, Human, Human + Guinea Pig, Human + Hamster, Human + Mouse, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 化学趋化 免疫系统 神经生物学 创伤修复 product.subtitle.recentcitations 第一作者 Bouhaddou, M 标题 The Global Phosphorylation Landscape of SARS-CoV-2 Infection. 文献引用 Cell; 182(3) pg685-712.e19 PubMed Id 32645325 第一作者 Lee, A W 标题 A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. 文献引用 The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 第一作者 Alenazi, Y 标题 Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. 文献引用 Scientific Reports; 8(1) pg6333 PubMed Id 29679010 product.subtitle.productreviews 现有评论 Useful for western blot antibody validation Yielded a clean band at the expected molecular weight (~11kDa). 来自: Anthony | 日期: 2020/7/10 × Useful for western blot antibody validation Yielded a clean band at the expected molecular weight (~11kDa). 来自: Anthony | 日期: 2020/7/10 Close
