Recombinant Murine Eotaxin-2 (CCL24) 0 评论Submit a Review 产品详情 产品编号： 250-22 产品描述： Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3, including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 amino acid residues for the murine homolog, without C-terminal truncation). Eotaxin-2 contains the four conserved cysteine residues present in CC chemokines. Recombinant Murine Eotaxin-2 is a 10.3 kDa protein containing 93 amino acid residues. Source: E.coli Synonyms: CCL24, MPIF-2, CkB-6 AA Sequence: VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100 ng/ml. Calculated Molecular Weight: 10.3 kDa Accession Number: Q9JKC0 Gene ID: 56221 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 化学趋化 免疫系统 创伤修复 product.subtitle.recentcitations 第一作者 Felton, J M 标题 Aiolos regulates eosinophil migration into tissues 文献引用 Mucosal Immunology; 14(6) pg1271-1281 PubMed Id 34341502 第一作者 Patial, S 标题 Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. 文献引用 Scientific Reports; 11(1) pg15465 PubMed Id 34326406 第一作者 Karcz, T P 标题 UDP-glucose and P2Y14 receptor amplify allergen-induced airway eosinophilia. 文献引用 The Journal of Clinical Investigation; 131(7) PubMed Id 33792561
