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趋化因子

Recombinant Murine Exodus-2 (CCL21)

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产品详情

产品编号: 250-13
产品描述:
Recombinant Murine Exodus-2 (CCL21)

Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Murine Exodus-2 is a 12.0 kDa protein containing 110 amino acid residues.

Source: E.coli

Synonyms: CCL21, 6Ckine, SLC

AA Sequence: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10.0-100.0 ng/ml.

Recombinant Murine Exodus-2 (CCL21) Biological Activity Graph

Calculated Molecular Weight: 12 kDa

Accession Number: P86793

Gene ID: 65956

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Chang, M H
标题
Arthritis flares mediated by tissue-resident memory T cells in the joint.
文献引用
Cell Reports; 37(4) pg109902
PubMed Id
第一作者
Arasa, J
标题
Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation.
文献引用
The Journal of Experimental Medicine; 218(7)
PubMed Id
第一作者
Riegel, K
标题
RAF kinases are stabilized and required for dendritic cell differentiation and function
文献引用
Cell Death and Differentiation; 27(4) pg1300-1315
PubMed Id