Recombinant Human Eotaxin (CCL11) 1 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 300-21 Descripcion Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL11 AA Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0 ng/ml. Calculated Molecular Weight: 8.3 kDa Accession Number: P51671 Gene ID: 6356 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Guinea Pig, Human, Human + Guinea Pig, Human + Hamster, Human + Mouse, Mouse, Rat References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Neurobiology Wound Healing product.subtitle.recentcitations Primer autor Bouhaddou, M Titulo The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Citar Cell; 182(3) pg685-712.e19 PudMed id 32645325 Primer autor Lee, A W Titulo A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citar The Journal of Biological Chemistry; 294(29) pg11199-11212 PudMed id 31167786 Primer autor Alenazi, Y Titulo Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citar Scientific Reports; 8(1) pg6333 PudMed id 29679010 product.subtitle.productreviews Comentarios existentes Useful for western blot antibody validation Yielded a clean band at the expected molecular weight (~11kDa). De: Anthony | Fecha: 10/07/2020 × Useful for western blot antibody validation Yielded a clean band at the expected molecular weight (~11kDa). De: Anthony | Fecha: 10/07/2020 Close