Recombinant Human Eotaxin-3 (CCL26) 0 리뷰Submit a Review 제품 상세 카다로그 번호 300-48 제품 설명 Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant Human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL26, Small-inducible cytokine A26, Thymic stroma chemokine-1 (TSC-1) AA Sequence: TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human CCR3/HEK293 cells. The maximum activity was achieved at 2ug/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: Q9Y258 Gene ID: 10344 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations 제 1 저자 Lee, A W 주제 A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. 인용 The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed ID 31167786 제 1 저자 Alenazi, Y 주제 Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. 인용 Scientific Reports; 8(1) pg6333 PubMed ID 29679010 제 1 저자 Singh, K 주제 Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. 인용 Scientific Reports; 7(1) pg4267 PubMed ID 28655871
