Recombinant Murine CXCL16 0 리뷰Submit a Review 제품 상세 카다로그 번호 250-28 제품 설명 CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues, including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal mucin-like stalk sequence. The extracellular domain contains 89 amino acid residues (86 a.a. residues for the murine homolog). Recombinant Murine CXCL16 is a 9.9 kDa protein containing 88 amino acid residues. Source: E.coli Synonyms: SRPSOX AA Sequence: NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine lymphocytes using a concentration of 20-1000 ng/ml. Calculated Molecular Weight: 9.9 kDa Accession Number: Q8BSU2 Gene ID: 66102 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human + Mouse, Mouse References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations 제 1 저자 Di Pilato, M 주제 CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment. 인용 Cell; 184(17) pg4512-4530.e22 PubMed ID 34343496 제 1 저자 Lesch, S 주제 T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. 인용 Nature Biomedical Engineering; PubMed ID 34083764 제 1 저자 Jacob, N 주제 Butyrate induced Tregs are capable of migration from the GALT to the pancreas to restore immunological tolerance during type-1 diabetes 인용 Scientific Reports; 10(1) pg19120 PubMed ID 33154424