Animal-Free Recombinant Human BMP-4 (E.coli derived) 1 리뷰submitareview 제품 상세 카다로그 번호 AF-120-05ET 제품 설명 Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 107 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor, and includes a N-terminal Met residue. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 24.2 kDa. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Bone Morphogenetic Protein-4, BMP-2B, DVR4 AA Sequence (monomer): MKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml. Calculated Molecular Weight: 23.9 kDa Accession Number: P12644 Gene ID: 652 Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse, Rat, Salamander Research Interest Organoids Angiogenesis/Cardiovascular Apoptosis Bone, Skeletal, Cartilage Cell Culture Immune System Neurobiology Stem Cells & Differentiation TGF-β Superfamily References PubMed SDS Product Line Country Of Origin: USA Not for human use. product.subtitle.productreviews 기존 리뷰 BMP4 reliable product for my differentiation protocols that was easy to reconstitute and adjust dosage! 에서: Eman | 날짜: 2020-07-15 × BMP4 reliable product for my differentiation protocols that was easy to reconstitute and adjust dosage! 에서: Eman | 날짜: 2020-07-15 Close