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Growth Factors & Cytokines

Recombinant Human BMP-4 (HeLa derived)

제품 상세

카다로그 번호 120-05
제품 설명

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant Human BMP-4, expressed in HeLa cells, is a 25.6 kDa homodimeric glycoprotein.

Source: HeLa cells

Synonyms: Bone Morphogenetic Protein-4, BMP-2B, DVR4

AA Sequence (monomer): HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR

Purity: ≥ 97% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml.

Calculated Molecular Weight: 25.6 kDa

Accession Number: P12644

Gene ID: 652

Note:

100μg is the largest vial size for this product.
Larger sizes supplied as multiple 50μg and/or 100μg vials.

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.

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기존 리뷰
High-yield iPSC differentiation!
When differentiating stem cells, I always turn to Peprotech for ordering my growth factors (like BMP4). They stay stable for long periods of time under the recommended storage conditions. And they hold up well in the differentiation media, because I get good differentiation results without excessive cell death. Results are consistent between differentiations, so I appreciate this reproducibility. ... reviews.showmore
에서:  Kendall | 날짜:  2020-08-26