Recombinant Human Eotaxin (CCL11) 1 리뷰Submit a Review 제품 상세 카다로그 번호 300-21 제품 설명 Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Human Eotaxin is an 8.3 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL11 AA Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0 ng/ml. Calculated Molecular Weight: 8.3 kDa Accession Number: P51671 Gene ID: 6356 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Guinea Pig, Human, Human + Guinea Pig, Human + Hamster, Human + Mouse, Mouse, Rat References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Neurobiology Wound Healing product.subtitle.recentcitations 제 1 저자 Bouhaddou, M 주제 The Global Phosphorylation Landscape of SARS-CoV-2 Infection. 인용 Cell; 182(3) pg685-712.e19 PubMed ID 32645325 제 1 저자 Lee, A W 주제 A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. 인용 The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed ID 31167786 제 1 저자 Alenazi, Y 주제 Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. 인용 Scientific Reports; 8(1) pg6333 PubMed ID 29679010 product.subtitle.productreviews 기존 리뷰 Useful for western blot antibody validation Yielded a clean band at the expected molecular weight (~11kDa). 에서: Anthony | 날짜: 2020-07-10 × Useful for western blot antibody validation Yielded a clean band at the expected molecular weight (~11kDa). 에서: Anthony | 날짜: 2020-07-10 Close