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Growth Factors & Cytokines

Recombinant Human FGF-19

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제품 상세

카다로그 번호 100-32
제품 설명
Recombinant Human FGF-19

The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high-affinity heparin-dependent ligand for FGFR4. FGF-19 is expressed during brain development and embryogenesis. Recombinant Human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-19, FGFJ

AA Sequence: MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml.

Calculated Molecular Weight: 21.8 kDa

Accession Number: O95750

Gene ID: 9965

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Nguyen, V V
주제
A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles.
인용
Journal Of Extracellular Vesicles; 11(11) pge12280
PubMed ID
제 1 저자
Li, P
주제
Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids.
인용
Science Advances; 8(3) pgeabj5908
PubMed ID
제 1 저자
Clark, M P
주제
Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models
인용
Cell Death & Disease; 12(7) pg641
PubMed ID