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Growth Factors & Cytokines

Recombinant Human FGF-5

제품 상세

카다로그 번호 100-34
제품 설명

FGF-5 is a secreted, heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant Human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-5, HBGF-5, Smag-82

AA Sequence: MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

Calculated Molecular Weight: 27.6 kDa

Accession Number: P12034

Gene ID: 2250

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.