Recombinant Human G-CSF 0 리뷰Submit a Review 제품 상세 카다로그 번호 300-23 제품 설명 G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues. Source: E.coli Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin AA Sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPW APLSSCPSQA LQLAGCLSQL HSGLFLYQGL LQALEGISPE LG PTLDTL QLDVADFATT IWQQMEELGM APALQPTQGA MPAFASAFQR RAGG VLVA SHLQSFLEVS YRVLRHLAQP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 18.7 kDa Accession Number: P09919 Gene ID: 1440 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Human + Mouse, Human + Virus, Monkey, Mouse, Pig, Plant References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Angiogenesis/Cardiovascular Cancer Diabetes/Weight Regulation Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations 제 1 저자 Loef, E J 주제 Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses. 인용 The Journal of Biological Chemistry; 298(7) pg102112 PubMed ID 35690148 제 1 저자 Díaz de la Guardia, R 주제 Engraftment characterization of risk-stratified AML in NSGS mice. 인용 Blood Advances; 5(23) pg4842-4854 PubMed ID 34470043 제 1 저자 Bent, E H 주제 Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy. 인용 Nature Communications; 12(1) pg6218 PubMed ID 34711820