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Growth Factors & Cytokines

Recombinant Human GDF-7

제품 상세

카다로그 번호 120-37
제품 설명

GDF-7 belongs to the TGF-β superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissues. Recombinant Human GDF-7 is a 28.0 kDa disulfide-linked homodimer containing two 129 amino acid residues.

Source: E.coli

Synonyms: Growth/Differentiation Factor-7, BMP-12

AA Sequence (monomer): TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.

Calculated Molecular Weight: 28 kDa

Accession Number: Q7Z4P5

Gene ID: 151449

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.