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Neurotrophins

Recombinant Human GMF-β

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제품 상세

카다로그 번호 450-37
제품 설명
Recombinant Human GMF-β

GMF-β is a brain-specific protein that belongs to the actin-binding proteins ADF structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto immune diseases, possibly through its ability to induce the production and secretion of various pro inflammatory cytokines. Recombinant Human GMF-β is a 16.5 kDa globular protein containing 141 amino acid residues, including one intramolecular disulfide bond.

Source: E.coli

Synonyms: Glia Maturation Factor beta, GMFB

AA Sequence: SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

Calculated Molecular Weight: 16.5 kDa

Accession Number: P60983

Gene ID: 2764

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Di Giorgio, F P
주제
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
인용
Cell Stem Cell; 3(6) pg637-48
PubMed ID