Recombinant Human IFN-γ 0 리뷰submitareview 제품 상세 카다로그 번호 300-02 제품 설명 IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues. Source: E.coli Synonyms: Immune Interferon, type II interferon, T cell interferon, MAF AA Sequence: MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Assay #1: Determined by its ability to induce STAT1/STAT2 activation in Human COLO 205 ISRE LUC reporter cells. Assay #2: The ED50 determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. Calculated Molecular Weight: 16.8 kDa Accession Number: P01579.1 Gene ID: 3458 crossreactivity: Bacteria, Fish + Virus, Human, Human + Bacteria, Human + Hamster, Human + Mouse, Human + Virus, Mandarin Fish, Monkey, Mouse, Pig, Rabbit, Rat Research Interest AIDS/HIV Angiogenesis/Cardiovascular Cancer Diabetes/Weight Regulation Immune System Neurobiology Stem Cells & Differentiation Allergy Transplantation References PubMed SDS Product Line Country Of Origin: USA Not for human use.
