Recombinant Human IFN-β 0 리뷰submitareview 제품 상세 카다로그 번호 300-02BC 제품 설명 Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. PeproTech’s Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFN-β has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry. *Human IFN-β (Catalog Number 300-02BC) has replaced Human IFN-β (Catalog Number 300-02B) Source: CHO cells Synonyms: Fibroblast Interferon, IFNB1, Type I Interferon AA Sequence: MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cytotoxicity assay using human TF-1 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Calculated Molecular Weight: 20 kDa Accession Number: P01574 Gene ID: 3456 Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Monkey, Mouse, Pig Research Interest AIDS/HIV Cancer Immune System Neurobiology References PubMed SDS Product Line Country Of Origin: USA Not for human use.
