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Animal-Free Cytokines

Animal-Free Recombinant Human IL-2

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제품 상세

카다로그 번호 AF-200-02
제품 설명
Animal-Free Recombinant Human IL-2

IL-2 is a powerful immunoregulatory lymphokine produced by T cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Interleukin-2, T-cell growth factor (TCGF), Aldesleukin

AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.

Animal-Free Recombinant Human IL-2 Biological Activity Graph

Calculated Molecular Weight: 15.5 kDa

Accession Number: P60568

Gene ID: 3558

Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Laucirica, D R
주제
Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection.
인용
Immunology and Cell Biology; 100(5) pg352-370
PubMed ID
제 1 저자
Freed-Pastor, W A
주제
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer.
인용
Cancer Cell; 39(10) pg1342-1360.e14
PubMed ID
제 1 저자
Inano, T
주제
Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia
인용
Scientific Reports; 11(1) pg17702
PubMed ID