Recombinant Human IL-20 0 리뷰Submit a Review 제품 상세 카다로그 번호 200-20 제품 설명 IL-20 is a member of the IL-10 family of regulatory cytokines, which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20Rα and type II IL-20Rβ. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant Human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains. Source: E.coli Synonyms: Interleukin-20, Cytokine ZCYTO10 AA Sequence (monomer): MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to activate STAT following receptor ligand interaction. Calculated Molecular Weight: 35.2 kDa Accession Number: Q9NYY1 Gene ID: 50604 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Immune System Inflammation Allergy product.subtitle.recentcitations 제 1 저자 Schilling, B 주제 IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells. 인용 PLoS ONE; 8(2) pge47234 PubMed ID 23408925 제 1 저자 Zenewicz, L A 주제 Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. 인용 Immunity; 29(6) pg947-57 PubMed ID 19100701