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Chemokines

Recombinant Human IL-8 (CXCL8) (72 a.a.)

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제품 상세

카다로그 번호 200-08M
제품 설명
Recombinant Human IL-8 (CXCL8) (72 a.a.)

IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues.

Source: E.coli

Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1

AA Sequence: SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.

Recombinant Human IL-8 (CXCL8) (72 a.a.) Biological Activity Graph

Calculated Molecular Weight: 8.4 kDa

Accession Number: P10145

Gene ID: 3576

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Cai, B
주제
N2-Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle.
인용
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 8(19) pge2100584
PubMed ID
제 1 저자
Arif, N
주제
PECAM-1 supports leukocyte diapedesis by tension-dependent dephosphorylation of VE-cadherin.
인용
The EMBO Journal; 40(9) pge106113
PubMed ID
제 1 저자
Miao, L
주제
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
인용
Clinical And Translational Medicine; 11(4) pge395
PubMed ID