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Chemokines

Recombinant Human IL-8 (CXCL8) (77 a.a.)

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제품 상세

카다로그 번호 200-08
제품 설명
Recombinant Human IL-8 (CXCL8) (77 a.a.)

IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (CXCL8) (77 a.a.) (endothelial-derived) is an 8.9 kDa protein containing 77 amino acid residues.

Source: E.coli

Synonyms: Interleukin-8, CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1

AA Sequence: AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25.0-150.0 ng/ml.

Recombinant Human IL-8 (CXCL8) (77 a.a.) Biological Activity Graph

Calculated Molecular Weight: 8.9 kDa

Accession Number: P10145

Gene ID: 3576

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Jain, P
주제
Reconstruction of Ultra-thin Alveolar-capillary Basement Membrane Mimics.
인용
Advanced Biology; 5(8) pge2000427
PubMed ID
제 1 저자
Wang, W
주제
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
인용
Nature Communications; 12(1) pg4441
PubMed ID
제 1 저자
Ocaña-Guzmán, R
주제
Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity.
인용
Journal Of Immunology Research; 2021 pg6654220
PubMed ID