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Chemokines

Recombinant Human MCP-4 (CCL13)

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제품 상세

카다로그 번호 300-24
제품 설명
Recombinant Human MCP-4 (CCL13)

The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-4 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

Synonyms: Monocyte Chemotactic Protein-4, CCL13, NCC-1

AA Sequence: QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml.

Recombinant Human MCP-4 (CCL13) Biological Activity Graph

Calculated Molecular Weight: 8.6 kDa

Accession Number: Q99616

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Lee, A W
주제
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
인용
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed ID
제 1 저자
Alenazi, Y
주제
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
인용
Scientific Reports; 8(1) pg6333
PubMed ID
제 1 저자
Singh, K
주제
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
인용
Scientific Reports; 7(1) pg4267
PubMed ID