Recombinant Human NT-4 0 리뷰submitareview 제품 상세 카다로그 번호 450-04 제품 설명 NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta, and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors, and promotes the survival of peripheral sensory sympathetic neurons. Recombinant Human NT-4 is a noncovalently linked homodimer of two 14.0 kDa polypeptide monomers (260 total amino acid residues). Source: E.coli Synonyms: Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5) AA Sequence (monomer): GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml. Calculated Molecular Weight: 28.1 kDa Accession Number: P34130 Gene ID: 4909 crossreactivity: Frog, Human, Mouse, Rat Research Interest Diabetes/Weight Regulation Neurobiology Stem Cells & Differentiation References PubMed SDS Product Line Country Of Origin: USA Not for human use.