PeproTech is proud to be able to continue to support you in the midst of unprecedented challenges pertaining to the COVID-19 virus. For more information, click here.

Growth Factors & Cytokines

Recombinant Human Relaxin-3

제품 상세

카다로그 번호 130-10
제품 설명

Relaxin-3 is a secreted protein structurally related to insulin that is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or “angiotensin-like” peptide receptor, and has also been identified for binding specifically to the LGR7 receptor, previously identified as an “orphan” G protein-coupled receptor. Signaling by relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats. Recombinant Human Relaxin-3 is a 5.5 kDa, disulfide-linked, heterodimeric protein consisting of a 24 amino acid A-chain and a 27 amino acid B-chain.

Source: E.coli

Synonyms: H3 relaxin, Insulin-like peptide-7, INSL7

AA Sequence: Alpha chain: DVLAGLSSSC CKWGCSKSEI SSLC
Beta chain: RAAPYGVRLC GREFIRAVIF TCGGSRW

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

Calculated Molecular Weight: 5.5 kDa

Accession Number: Q8WXF3

Gene ID: 117579

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.