Recombinant Human sCD27 Ligand 0 리뷰Submit a Review 제품 상세 카다로그 번호 310-30 제품 설명 CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes, as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. PeproTech’s Recombinant Human sCD27L contains the extracellular domain plus an N-terminal His-Tag. The calculated molecular weight of Recombinant Human sCD27L is 18.8 kDa. Source: CHO cells Synonyms: soluble CD27 Ligand, CD27L, TNFSF7, CD70 AA Sequence: HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors. Calculated Molecular Weight: 18.8 kDa Accession Number: P32970 Gene ID: 970 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Immune System TNF Superfamily
