Recombinant Human SDF-1α (CXCL12)

제품 상세

카다로그 번호 300-28A

제품 설명

SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues.

Source: E.coli

Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF

AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 20-80 ng/ml.

Cross Reactivity:

Bacteria, Cow, Dog, Hamster, Human , Human + Monkey, Human + Mouse, Human + Pig, Leech, Monkey, Mouse, Rat

Research Interest

Stem Cells & Differentiation

Country Of Origin: USA

Not for human use.

First Author

Title

Citation

Pubmed

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Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns.

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Opioids trigger alpha 5 beta 1 integrin-mediated monocyte adhesion.

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Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus.

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Despite inhibition of hematopoietic progenitor cell growth in vitro, the tyrosine kinase inhibitor imatinib does not impair engraftment of human CD133+ cells into NOD/SCIDbeta2mNull mice.

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0 Jul 2006

16614006
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The chemokine SDF-1/CXCL12 modulates the firing pattern of vasopressin neurons and counteracts induced vasopressin release through CXCR4.

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23 May 2006

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The metastasis-associated 67-kDa laminin receptor is involved in G-CSF-induced hematopoietic stem cell mobilization.

Blood; 108(7) pg2476-84

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Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability.

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A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development.

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4 Sep 2006

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WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.

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1 Jan 2007

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Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.

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Structure/function relationships of CCR8 agonists and antagonists. Amino-terminal extension of CCL1 by a single amino acid generates a partial agonist.

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1 Dec 2006

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

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CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells.

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Braun, D

Semimature stage: a checkpoint in a dendritic cell maturation program that allows for functional reversion after signal-regulatory protein-alpha ligation and maturation signals.

Journal of immunology (Baltimore, Md. : 1950); 177(12) pg8550-9

15 Dec 2006

17142753
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Martin, S K

Tumor angiogenesis is associated with plasma levels of stromal-derived factor-1alpha in patients with multiple myeloma.

Clinical cancer research : an official journal of the American Association for Cancer Research; 12(23) pg6973-7

1 Dec 2006

17145816
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Ries, C

MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines.

Blood; 109(9) pg4055-63

1 May 2007

17197427
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Yang, L

Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo.

Cancer Research; 67(2) pg651-8

15 Jan 2007

17234775
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DiVietro, J A

Immobilized stromal cell-derived factor-1alpha triggers rapid VLA-4 affinity increases to stabilize lymphocyte tethers on VCAM-1 and subsequently initiate firm adhesion.

Journal of immunology (Baltimore, Md. : 1950); 178(6) pg3903-11

15 Mar 2007

17339490
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Proost, P

Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration.

Blood; 110(1) pg37-44

1 Jul 2007

17363734
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Ponte, A L

The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.

Stem cells (Dayton, Ohio); 25(7) pg1737-45

0 Jul 2007

17395768
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Hung, S

Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo.

PLoS ONE; 2(5) pge416

2 May 2007

17476338
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Ao, M

Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.

Cancer Research; 67(9) pg4244-53

1 May 2007

17483336
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Agrawal, A

Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway.

Journal of immunology (Baltimore, Md. : 1950); 178(11) pg6912-22

1 Jun 2007

17513740
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Glodek, A M

Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells.

Leukemia; 21(8) pg1723-32

0 Aug 2007

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De La Luz Sierra, M

Transcription factor Gfi-1 induced by G-CSF is a negative regulator of CXCR4 in myeloid cells.

Blood; 110(7) pg2276-85

1 Oct 2007

17596540
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Rosenkilde, M M

Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor.

The Journal of Biological Chemistry; 282(37) pg27354-65

14 Sep 2007

17599916
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Kawai, T

Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells.

Stem Cells and Development; 16(3) pg361-70

0 Jun 2007

17610366
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Ghandour, H

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion.

Blood; 110(10) pg3682-90

15 Nov 2007

17702895
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Chen, Y

Prostaglandin D2 suppresses human NK cell function via signaling through D prostanoid receptor.

Journal of immunology (Baltimore, Md. : 1950); 179(5) pg2766-73

1 Sep 2007

17709490
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Sierro, F

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.

Proceedings of the National Academy of Sciences of the United States of America; 104(37) pg14759-64

11 Sep 2007

17804806
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Warrington, N M

Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.

Cancer Research; 67(18) pg8588-95

15 Sep 2007

17875698
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Zlei, M

Characterization of in vitro growth of multiple myeloma cells.

Experimental Hematology; 35(10) pg1550-61

0 Oct 2007

17889722
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Miao, Z

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature.

Proceedings of the National Academy of Sciences of the United States of America; 104(40) pg15735-40

2 Oct 2007

17898181
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Fuhler, G M

Reduced activation of protein kinase B, Rac, and F-actin polymerization contributes to an impairment of stromal cell derived factor-1 induced migration of CD34+ cells from patients with myelodysplasia.

Blood; 111(1) pg359-68

1 Jan 2008

17898317
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Haynes, N M

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

Journal of immunology (Baltimore, Md. : 1950); 179(8) pg5099-108

15 Oct 2007

17911595
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Fagerli, U

Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.

Blood; 111(2) pg806-15

15 Jan 2008

17934070
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Bhandari, D

Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.

The Journal of Biological Chemistry; 282(51) pg36971-9

21 Dec 2007

17947233
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Norling, L V

Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology; 22(3) pg682-90

0 Mar 2008

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Stanley, P

Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell.

The EMBO Journal; 27(1) pg62-75

9 Jan 2008

18079697
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Lim, H W

Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 180(1) pg122-9

1 Jan 2008

18097011
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Bristow, C L

NF-kappaB signaling, elastase localization, and phagocytosis differ in HIV-1 permissive and nonpermissive U937 clones.

Journal of immunology (Baltimore, Md. : 1950); 180(1) pg492-9

1 Jan 2008

18097051
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Lacalle, R A

Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement.

The Journal of Cell Biology; 179(7) pg1539-53

31 Dec 2007

18158329
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Yang, D

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses.

The Journal of Experimental Medicine; 205(1) pg79-90

21 Jan 2008

18195069
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Bernardini, G

CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets.

Blood; 111(7) pg3626-34

1 Apr 2008

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Valiathan, R R

Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag.

Virology Journal; 5 pg23

11 Feb 2008

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Pawelczyk, E

In vitro model of bromodeoxyuridine or iron oxide nanoparticle uptake by activated macrophages from labeled stem cells: implications for cellular therapy.

Stem cells (Dayton, Ohio); 26(5) pg1366-75

0 May 2008

18276802
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Marquez-Curtis, L

Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of stromal cell-derived factor-1alpha: another player in hematopoietic stem/progenitor cell mobilization?

Stem cells (Dayton, Ohio); 26(5) pg1211-20

0 May 2008

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Li, J

Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro.

World Journal of Gastroenterology; 14(15) pg2308-13

21 Apr 2008

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de la Rosa, G

Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.

Journal of immunology (Baltimore, Md. : 1950); 180(10) pg6868-76

15 May 2008

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Bogani, C

Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis.

Stem cells (Dayton, Ohio); 26(8) pg1920-30

0 Aug 2008

18511598
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Stefanidakis, M

Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro.

Blood; 112(4) pg1280-9

15 Aug 2008

18524990
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Zhang, X

Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A.

Blood; 112(5) pg1683-6

1 Sep 2008

18565850
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Wolf, R

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.

Journal of immunology (Baltimore, Md. : 1950); 181(2) pg1499-506

15 Jul 2008

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Contento, R L

CXCR4-CCR5: a couple modulating T cell functions.

Proceedings of the National Academy of Sciences of the United States of America; 105(29) pg10101-6

22 Jul 2008

18632580
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Meditz, A L

SDF-1alpha is a potent inducer of HIV-1-Specific CD8+ T-cell chemotaxis, but migration of CD8+ T cells is impaired at high viral loads.

AIDS Research and Human Retroviruses; 24(7) pg977-85

0 Jul 2008

18671480
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Mancino, A

Divergent effects of hypoxia on dendritic cell functions.

Blood; 112(9) pg3723-34

1 Nov 2008

18694997
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Barbieri, F

Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas.

Clinical cancer research : an official journal of the American Association for Cancer Research; 14(16) pg5022-32

15 Aug 2008

18698020
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Secchiero, P

Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells.

Stem cells (Dayton, Ohio); 26(11) pg2955-63

0 Nov 2008

18772312
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Elagib, K E

Cross-talk of GATA-1 and P-TEFb in megakaryocyte differentiation.

Blood; 112(13) pg4884-94

15 Dec 2008

18780834
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Vassiliou, E K

Bone marrow-derived dendritic cells generated in the presence of resolvin E1 induce apoptosis of activated CD4+ T cells.

Journal of immunology (Baltimore, Md. : 1950); 181(7) pg4534-44

1 Oct 2008

18802056
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Malik, M

Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase.

Journal of immunology (Baltimore, Md. : 1950); 181(7) pg4632-7

1 Oct 2008

18802065
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Shiow, L R

The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.

Nature Immunology; 9(11) pg1307-15

0 Nov 2008

18836449
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Ghosh, M C

Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck.

Blood; 113(3) pg575-84

15 Jan 2009

18840710
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McGettrick, H M

Direct observations of the kinetics of migrating T cells suggest active retention by endothelial cells with continual bidirectional migration.

Journal of Leukocyte Biology; 85(1) pg98-107

0 Jan 2009

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Ito, A

Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue.

The Journal of Biological Chemistry; 283(51) pg35715-23

19 Dec 2008

18977759
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Mines, M A

Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation.

The Journal of Biological Chemistry; 284(9) pg5742-52

27 Feb 2009

19106094
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Frascaroli, G

Human cytomegalovirus paralyzes macrophage motility through down-regulation of chemokine receptors, reorganization of the cytoskeleton, and release of macrophage migration inhibitory factor.

Journal of immunology (Baltimore, Md. : 1950); 182(1) pg477-88

1 Jan 2009

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Vagima, Y

MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization.

The Journal of Clinical Investigation; 119(3) pg492-503

0 Mar 2009

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Egesten, A

SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.

PLoS ONE; 4(3) pge4769

0 2009

19274094
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Viard, M

Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death.

BMC Cell Biology; 10 pg21

26 Mar 2009

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Schneider, O D

Pertussis toxin signals through the TCR to initiate cross-desensitization of the chemokine receptor CXCR4.

Journal of immunology (Baltimore, Md. : 1950); 182(9) pg5730-9

1 May 2009

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Palumbo, R

Src family kinases are necessary for cell migration induced by extracellular HMGB1.

Journal of Leukocyte Biology; 86(3) pg617-23

0 Sep 2009

19401391
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Gollmer, K

CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.

Blood; 114(3) pg580-8

16 Jul 2009

19451552
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Ghosh, M C

Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration.

Blood; 114(7) pg1366-73

13 Aug 2009

19520808
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Izhak, L

A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.

Journal of immunology (Baltimore, Md. : 1950); 183(1) pg732-9

1 Jul 2009

19535619
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Kawaguchi, A

Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice.

Blood; 114(14) pg2961-8

1 Oct 2009

19657116
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Urbinati, C

HIV-1 Tat and heparan sulfate proteoglycan interaction: a novel mechanism of lymphocyte adhesion and migration across the endothelium.

Blood; 114(15) pg3335-42

8 Oct 2009

19661268
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Chang, Y

p210(Bcr-Abl) desensitizes Cdc42 GTPase signaling for SDF-1alpha-directed migration in chronic myeloid leukemia cells.

Oncogene; 28(46) pg4105-15

19 Nov 2009

19718053
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Costantini, J L

TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia.

Blood; 114(21) pg4703-12

19 Nov 2009

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Nanki, T

Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis.

Arthritis research & therapy; 11(5) pgR149

0 2009

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Trinidad, E M

An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression.

Blood; 114(24) pg5081-90

3 Dec 2009

19828693
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Sordi, V

Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function.

Stem cells (Dayton, Ohio); 28(1) pg140-51

0 Jan 2010

19924826
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Sekine, Y

Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells.

Journal of immunology (Baltimore, Md. : 1950); 183(12) pg7966-74

15 Dec 2009

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McCormick, P J

Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor.

PLoS ONE; 4(12) pge8102

1 Dec 2009

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Cook, A

Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons.

The Journal of Biological Chemistry; 285(14) pg10563-71

2 Apr 2010

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Madigan, J

Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients.

Journal of immunology (Baltimore, Md. : 1950); 184(6) pg3202-12

15 Mar 2010

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Sierra, M I

AMSH interacts with ESCRT-0 to regulate the stability and trafficking of CXCR4.

The Journal of Biological Chemistry; 285(18) pg13990-4004

30 Apr 2010

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Saini, V

CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin.

The Journal of Biological Chemistry; 285(20) pg15566-76

14 May 2010

20228059
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Berge, T

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

PLoS ONE; 5(3) pge9761

18 Mar 2010

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Zheng, K

Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells.

Journal of experimental & clinical cancer research : CR; 29 pg31

11 Apr 2010

20380740
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Bullock, G C

Iron control of erythroid development by a novel aconitase-associated regulatory pathway.

Blood; 116(1) pg97-108

8 Jul 2010

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Wang, F

Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha.

BMC Neuroscience; 11 pg52

26 Apr 2010

20420688
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McGettrick, H M

Stromal cells differentially regulate neutrophil and lymphocyte recruitment through the endothelium.

Immunology; 131(3) pg357-70

0 Nov 2010

20518822
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Scielzo, C

HS1 has a central role in the trafficking and homing of leukemic B cells.

Blood; 116(18) pg3537-46

4 Nov 2010

20530793
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Jin, G

An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis.

PLoS ONE; 5(6) pge10993

8 Jun 2010

20544025
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Khan, M Z

CXCL12-mediated regulation of ANP32A/Lanp, a component of the inhibitor of histone acetyl transferase (INHAT) complex, in cortical neurons.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology; 6(1) pg163-70

0 Mar 2011

20617464
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Nijmeijer, S

The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges GÎ±i proteins, and constitutively impairs CXCR4 functioning.

The Journal of Biological Chemistry; 285(38) pg29632-41

17 Sep 2010

20622011
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Gorini, S

ATP secreted by endothelial cells blocks CXâ‚ƒCL 1-elicited natural killer cell chemotaxis and cytotoxicity via P2Yâ‚â‚ receptor activation.

Blood; 116(22) pg4492-500

25 Nov 2010

20668227
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Mandawat, A

Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists.

Blood; 116(24) pg5306-15

9 Dec 2010

20810927
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Foley, J F

Differentiation of human T cells alters their repertoire of G protein alpha-subunits.

The Journal of Biological Chemistry; 285(46) pg35537-50

12 Nov 2010

20829352
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Berlin, I

The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome.

The Journal of Biological Chemistry; 285(48) pg37895-908

26 Nov 2010

20876529
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Rigo, A

Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.

Molecular Cancer; 9 pg273

14 Oct 2010

20946648
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Gravel, S

The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: roles of receptor domains.

The Journal of Biological Chemistry; 285(49) pg37939-43

3 Dec 2010

20956518
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Zhukovsky, M A

Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes.

PLoS ONE; 5(10) pge13249

13 Oct 2010

20967243
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Zhang, H H

CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.

Journal of immunology (Baltimore, Md. : 1950); 185(11) pg6646-63

1 Dec 2010

20980630
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Rhodes, L V

Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk.

Molecular Cancer; 9 pg295

18 Nov 2010

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Yung, S C

Host chemokines bind to Staphylococcus aureus and stimulate protein A release.

The Journal of Biological Chemistry; 286(7) pg5069-77

18 Feb 2011

21138841
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Tchernychev, B

Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.

Proceedings of the National Academy of Sciences of the United States of America; 107(51) pg22255-9

21 Dec 2010

21139054
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Fang, J

Endogenous expression of matriptase in neural progenitor cells promotes cell migration and neuron differentiation.

The Journal of Biological Chemistry; 286(7) pg5667-79

18 Feb 2011

21149451
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Zhao, X

Active scaffolds for on-demand drug and cell delivery.

Proceedings of the National Academy of Sciences of the United States of America; 108(1) pg67-72

4 Jan 2011

21149682
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Thill, M

SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.

Molecular Vision; 17 pg85-98

10 Jan 2011

21245959
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Yoshida, N

CXCR4 expression on activated B cells is downregulated by CD63 and IL-21.

Journal of immunology (Baltimore, Md. : 1950); 186(5) pg2800-8

1 Mar 2011

21270405
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Bolton, M J

Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines.

Virology Journal; 8 pg45

31 Jan 2011

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de la Vega, M

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

Nature Communications; 2 pg259

29 Mar 2011

21448158
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Jham, B C

Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma.

PLoS ONE; 6(4) pge19103

29 Apr 2011

21559457
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Shin, J

Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1Î± in an Alzheimer's disease mouse model.

Stem cells (Dayton, Ohio); 29(7) pg1075-89

0 Jul 2011

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Greene, T A

Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.

PLoS ONE; 6(5) pge20123

0 2011

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Affentranger, S

Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes.

BMC Cell Biology; 12 pg28

22 Jun 2011

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Saini, V

The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1Î± function through distinct receptor interactions.

The Journal of Biological Chemistry; 286(38) pg33466-77

23 Sep 2011

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Malara, A

Extracellular matrix structure and nano-mechanics determine megakaryocyte function.

Blood; 118(16) pg4449-53

20 Oct 2011

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Chao, M P

Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy.

Blood; 118(18) pg4890-901

3 Nov 2011

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Xue, X

Structural basis of chemokine sequestration by CrmD, a poxvirus-encoded tumor necrosis factor receptor.

PLoS Pathogens; 7(7) pge1002162

0 Jul 2011

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Hyduk, S J

Talin-1 and kindlin-3 regulate alpha4beta1 integrin-mediated adhesion stabilization, but not G protein-coupled receptor-induced affinity upregulation.

Journal of immunology (Baltimore, Md. : 1950); 187(8) pg4360-8

15 Oct 2011

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Nasser, M W

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.

PLoS ONE; 6(9) pge23901

0 2011

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Munk, R

Involvement of mTOR in CXCL12 mediated T cell signaling and migration.

PLoS ONE; 6(9) pge24667

0 2011

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Trachtenberg, A

The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis.

BMC Research Notes; 4 pg396

11 Oct 2011

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Saini, V

Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction.

The Journal of Biological Chemistry; 286(51) pg44145-52

23 Dec 2011

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Schaeuble, K

Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration.

Journal of immunology (Baltimore, Md. : 1950); 187(11) pg5645-52

1 Dec 2011

22043010
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Yang, D

High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.

The Journal of Experimental Medicine; 209(1) pg157-71

16 Jan 2012

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O'Callaghan, K

Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.

Blood; 119(7) pg1717-25

16 Feb 2012

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Zoughlami, Y

Regulation of CXCR4 conformation by the small GTPase Rac1: implications for HIV infection.

Blood; 119(9) pg2024-32

1 Mar 2012

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Cui, Y

Stepwise optimization of the procedure for assessment of circulating progenitor cells in patients with myocardial infarction.

PLoS ONE; 7(1) pge30389

0 2012

22272341
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Bryant, J

CXCR4 and vascular cell adhesion molecule 1 are key chemokine/adhesion receptors in the migration of cytokine-activated T cells.

Arthritis and Rheumatism; 64(7) pg2137-46

0 Jul 2012

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Malik, R

Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.

The Journal of Biological Chemistry; 287(12) pg9013-27

16 Mar 2012

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Silvestrini, F

Differential adhesive properties of sequestered asexual and sexual stages of Plasmodium falciparum on human endothelial cells are tissue independent.

PLoS ONE; 7(2) pge31567

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CXCL12 mediates trophic interactions between endothelial and tumor cells in glioblastoma.

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Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells.

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Canals, M

Ubiquitination of CXCR7 controls receptor trafficking.

PLoS ONE; 7(3) pge34192

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Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells.

Journal of Translational Medicine; 10 pg68

2 Apr 2012

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Actin polymerization stabilizes Î±4Î²1 integrin anchors that mediate monocyte adhesion.

The Journal of Cell Biology; 197(1) pg115-29

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Matthews, D R

A multi-functional imaging approach to high-content protein interaction screening.

PLoS ONE; 7(4) pge33231

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Blood; 120(13) pg2620-30

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CXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin.

PLoS ONE; 7(4) pge34432

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L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950); 188(12) pg6357-70

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BMC Gastroenterology; 12 pg53

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Pulmonary CCL18 recruits human regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950); 189(1) pg128-37

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Rapid uptake and degradation of CXCL12 depend on CXCR7 carboxyl-terminal serine/threonine residues.

The Journal of Biological Chemistry; 287(34) pg28362-77

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Blood; 120(10) pg2076-86

6 Sep 2012

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The SDF-1Î±/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells.

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Blood; 120(8) pg1624-32

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Endothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivo.

Journal of immunology (Baltimore, Md. : 1950); 189(5) pg2553-62

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Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia.

Blood Cancer Journal; 1(2) pge4

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International Journal of Vascular Medicine; 2012 pg127149

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CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients.

BMC Medicine; 10 pg85

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PLoS ONE; 7(8) pge43665

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Evidence for chemokine-mediated coalescence of preformed flotillin hetero-oligomers in human T-cells.

The Journal of Biological Chemistry; 287(47) pg39664-72

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Differential regulation of bone marrow-derived endothelial progenitor cells and endothelial outgrowth cells by the Notch signaling pathway.

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Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12.

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Blood; 121(14) pg2704-14

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CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.

Journal of immunology (Baltimore, Md. : 1950); 190(7) pg3696-705

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The tandem PH domain-containing protein 2 (TAPP2) regulates chemokine-induced cytoskeletal reorganization and malignant B cell migration.

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Cysteine (C)-x-C receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells.

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Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by Epstein-Barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma.

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The Journal of Biological Chemistry; 288(23) pg16738-46

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Opposing chemokine gradients control human thymocyte migration in situ.

The Journal of Clinical Investigation; 123(5) pg2131-42

0 May 2013

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Epigenetic regulation of SOX9 by the NF-ÎºB signaling pathway in pancreatic cancer stem cells.

Stem cells (Dayton, Ohio); 31(8) pg1454-66

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The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis.

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Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice.

Journal of immunology (Baltimore, Md. : 1950); 191(1) pg97-109

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Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function.

The Journal of Biological Chemistry; 288(35) pg25173-82

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KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo.

Cell death & disease; 4 pge773

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Park, B

An isoform of C/EBPÎ², LIP, regulates expression of the chemokine receptor CXCR4 and modulates breast cancer cell migration.

The Journal of Biological Chemistry; 288(40) pg28656-67

4 Oct 2013

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Ponzetta, A

CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation.

Journal of immunology (Baltimore, Md. : 1950); 191(11) pg5684-94

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Pei, X

PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor 2.

Journal of immunology (Baltimore, Md. : 1950); 192(4) pg1878-86

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Yin, X

Lymphatic specific disruption in the fine structure of heparan sulfate inhibits dendritic cell traffic and functional T cell responses in the lymph node.

Journal of immunology (Baltimore, Md. : 1950); 192(5) pg2133-42

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Chemokine cooperativity is caused by competitive glycosaminoglycan binding.

Journal of immunology (Baltimore, Md. : 1950); 192(8) pg3908-3914

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Chwalek, K

Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models.

Scientific Reports; 4 pg4414

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Ong, S T

Phosphorylation of Rab5a protein by protein kinase CÏµ is crucial for T-cell migration.

The Journal of Biological Chemistry; 289(28) pg19420-34

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Borge, M

The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406.

Journal of immunology (Baltimore, Md. : 1950); 193(6) pg3165-74

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Duquenne, C

The two human CXCR4 isoforms display different HIV receptor activities: consequences for the emergence of X4 strains.

Journal of immunology (Baltimore, Md. : 1950); 193(8) pg4188-94

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Stephen, T L

Transforming growth factor Î²-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression.

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Tanenbaum, M E

A protein-tagging system for signal amplification in gene expression and fluorescence imaging.

Cell; 159(3) pg635-46

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DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.

The Journal of Experimental Medicine; 211(13) pg2549-66

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Ramos-Amaya, A

Survival of human circulating antigen-induced plasma cells is supported by plasma cell-niche cytokines and T follicular helper lymphocytes.

Journal of immunology (Baltimore, Md. : 1950); 194(3) pg1031-8

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Verma, R

The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR.

The Journal of Biological Chemistry; 290(11) pg6810-24

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Lourenco, S

Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.

Journal of immunology (Baltimore, Md. : 1950); 194(7) pg3463-74

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Mukovozov, I

The Neurorepellent Slit2 Inhibits Postadhesion Stabilization of Monocytes Tethered to Vascular Endothelial Cells.

Journal of immunology (Baltimore, Md. : 1950); 195(7) pg3334-44

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Yuzugullu, H

A PI3K p110Î²-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis.

Nature Communications; 6 pg8501

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Jain, N

Molecular difference between WASP and N-WASP critical for chemotaxis of T-cells towards SDF-1Î±.

Scientific Reports; 5 pg15031

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Dimeloe, S

The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions.

Journal of immunology (Baltimore, Md. : 1950); 196(1) pg106-14

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Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor.

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HIF-1Î± regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment.

Blood; 127(16) pg1987-97

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Coke, C J

Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression.

The Journal of Biological Chemistry; 291(19) pg9991-10005

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Wendt, E

Glucocorticoids Suppress CCR9-Mediated Chemotaxis, Calcium Flux, and Adhesion to MAdCAM-1 in Human T Cells.

Journal of immunology (Baltimore, Md. : 1950); 196(9) pg3910-9

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i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.

The Journal of Biological Chemistry; 291(24) pg12641-57

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Grimaldi, A

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages.

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Cytokine-like 1 Chemoattracts Monocytes/Macrophages via CCR2.

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Michlmayr, D

Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance.

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Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis.

Scientific Reports; 6 pg28378

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Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices.

Proceedings of the National Academy of Sciences of the United States of America; 113(35) pg9928-33

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The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5.

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Alekhina, O

Î²-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.

The Journal of Biological Chemistry; 291(50) pg26083-26097

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Benredjem, B

Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with Its Chemokine Ligands CXCL11 and CXCL12.

The Journal of Biological Chemistry; 292(1) pg31-42

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Phan, T X

Intrinsic Photosensitivity Enhances Motility of T Lymphocytes.

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LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.

The Journal of Experimental Medicine; 214(1) pg209-226

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Balsas, P

SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma.

Blood; 130(4) pg501-513

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Singh, K

Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.

Scientific Reports; 7(1) pg4267

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Hooshmand, M J

Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis.

Journal of immunology (Baltimore, Md. : 1950); 199(3) pg1069-1085

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Tripathi, P

Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-Î²1.

Stem Cell Reports; 9(2) pg667-680

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Isopeptide and ester bond ubiquitination both regulate degradation of the human dopamine receptor 4.

The Journal of Biological Chemistry; 292(52) pg21623-21630

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A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma.

Scientific Reports; 7(1) pg15038

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Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging.

The Journal of Biological Chemistry; 293(3) pg893-905

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Hinderer, S

Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells.

Scientific Reports; 8(1) pg110

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Senarath, K

GÎ³ identity dictates efficacy of GÎ²Î³ signaling and macrophage migration.

The Journal of Biological Chemistry; 293(8) pg2974-2989

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Shee, K

Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.

The Journal of Experimental Medicine; 215(3) pg895-910

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Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer.

Cancer Cell; 33(3) pg463-479.e10

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Mapping Interaction Sites on Human Chemokine Receptors by Deep Mutational Scanning.

Journal of immunology (Baltimore, Md. : 1950); 200(11) pg3825-3839

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Alenazi, Y

Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.

Scientific Reports; 8(1) pg6333

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Aurora A plays a dual role in migration and survival of human glioblastoma cells according to the CXCL12 concentration.

Oncogene; 38(1) pg73-87

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IL-33 Upregulates Cysteinyl Leukotriene Receptor Type 1 Expression in Human Peripheral Blood CD4

Journal of immunology (Baltimore, Md. : 1950); 201(9) pg2787-2798

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Convective forces increase CXCR4-dependent glioblastoma cell invasion in GL261 murine model.

Scientific Reports; 8(1) pg17057

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Hippo Pathway Kinase Mst1 Is Required for Long-Lived Humoral Immunity.

Journal of immunology (Baltimore, Md. : 1950); 202(1) pg69-78

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Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4.

The Journal of Experimental Medicine; 186(8) pg1383-8

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A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor.

The Journal of Experimental Medicine; 186(8) pg1395-400

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Disturbed CD4+ T cell homeostasis and in vitro HIV-1 susceptibility in transgenic mice expressing T cell line-tropic HIV-1 receptors.

The Journal of Experimental Medicine; 187(9) pg1439-49

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HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation.

Journal of immunology (Baltimore, Md. : 1950); 161(8) pg4309-17

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Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates.

Journal of Virology; 73(1) pg205-13

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Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74.

The Journal of Biological Chemistry; 274(2) pg956-61

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Delgado-Martín, C

Chemokine CXCL12 uses CXCR4 and a signaling core formed by bifunctional Akt, extracellular signal-regulated kinase (ERK)1/2, and mammalian target of rapamycin complex 1 (mTORC1) proteins to control chemotaxis and survival simultaneously in mature dendritic cells.

The Journal of Biological Chemistry; 286(43) pg37222-36

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Chávez-Vargas, L

Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING.

The Journal of Biological Chemistry; 291(12) pg6182-99

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Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.

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Chemokine receptor expression on infiltrating lymphocytes from abdominal aortic aneurysms: role of CXCR4-CXCL12 in lymphoid recruitment.

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Martínez-Muñoz, L

CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface.

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Antibacterial effect of microvesicles released from human neutrophilic granulocytes.

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Agonists for the Chemokine Receptor CXCR4.

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B cell depletion in immune thrombocytopenia reveals splenic long-lived plasma cells.

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Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis.

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Rodríguez-Bayona, B

STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion.

Journal of immunology (Baltimore, Md. : 1950); 191(10) pg4996-5004

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González-García, I

Increased survival is a selective feature of human circulating antigen-induced plasma cells synthesizing high-affinity antibodies.

Blood; 111(2) pg741-9

15 Jan 2008

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Rodríguez-Frade, J M

Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor.

The EMBO Journal; 23(1) pg66-76

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Sciumè, G

CX3CR1 expression defines 2 KLRG1+ mouse NK-cell subsets with distinct functional properties and positioning in the bone marrow.

Blood; 117(17) pg4467-75

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Décaillot, F M

CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.

The Journal of Biological Chemistry; 286(37) pg32188-97

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Hägerstrand, D

Characterization of an imatinib-sensitive subset of high-grade human glioma cultures.

Oncogene; 25(35) pg4913-22

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Rodríguez-Bayona, B

Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients.

Arthritis research & therapy; 12(3) pgR108

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Gérard, A

The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization.

The Journal of Cell Biology; 176(6) pg863-75

12 Mar 2007

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Gómez-Móuton, C

Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization.

Proceedings of the National Academy of Sciences of the United States of America; 98(17) pg9642-7

14 Aug 2001

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Delgado-Martín, C

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Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING.

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Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor.

The EMBO Journal; 23(1) pg66-76

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CX3CR1 expression defines 2 KLRG1+ mouse NK-cell subsets with distinct functional properties and positioning in the bone marrow.

Blood; 117(17) pg4467-75

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CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.

The Journal of Biological Chemistry; 286(37) pg32188-97

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Chemokine receptor expression on infiltrating lymphocytes from abdominal aortic aneurysms: role of CXCR4-CXCL12 in lymphoid recruitment.

Atherosclerosis; 200(2) pg264-70

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Martínez-Muñoz, L

CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface.

Proceedings of the National Academy of Sciences of the United States of America; 111(19) pgE1960-9

13 May 2014

24778234
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Röhrl, J

Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.

Journal of immunology (Baltimore, Md. : 1950); 184(12) pg6688-94

15 Jun 2010

20483750
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Timár, C I

Antibacterial effect of microvesicles released from human neutrophilic granulocytes.

Blood; 121(3) pg510-8

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Hägerstrand, D

Characterization of an imatinib-sensitive subset of high-grade human glioma cultures.

Oncogene; 25(35) pg4913-22

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Lefrançois, M

Agonists for the Chemokine Receptor CXCR4.

ACS Medicinal Chemistry Letters; 2(8) pg597-602

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