Recombinant Murine Eotaxin (CCL11) 0 리뷰Submit a Review 제품 상세 카다로그 번호 250-01 제품 설명 Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL11 AA Sequence: HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Murine Eotaxin was found to induce chemotaxis of purified eosinophils at concentrations ranging between 10-100 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P48298 Gene ID: 20292 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Neurobiology Wound Healing product.subtitle.recentcitations 제 1 저자 Felton, J M 주제 Aiolos regulates eosinophil migration into tissues 인용 Mucosal Immunology; 14(6) pg1271-1281 PubMed ID 34341502 제 1 저자 Patial, S 주제 Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. 인용 Scientific Reports; 11(1) pg15465 PubMed ID 34326406 제 1 저자 Dileepan, M 주제 Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A. 인용 Journal of Immunology; 204(3) pg682-693 PubMed ID 31871023
