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Growth Factors & Cytokines

Recombinant Murine IL-15

제품 상세

카다로그 번호 210-15
제품 설명

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.  IL-15 exerts its biological activities primarily on T cells.  It is also essential in the development, survival and activation of NK cells.  Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I.  Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.  Recombinant Murine IL-15 is a 13.3 kDa protein consisting of 115 amino acid residues.

Source: E.coli

Synonyms: IL-T

AA Sequence: MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 was determined by the stimulation of the proliferation of murine CTLL-2 cells is ≤ 5.0 ng/ml, corresponding to a specific activity of ≥ 2 x 105 units/mg.

Calculated Molecular Weight: 13.3 kDa

Accession Number: P48346

Gene ID: 16168

Note:

1mg will be provided as 2x500μg.

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.

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기존 리뷰
Product with great consistency
We have been using this cytokine for splenic NK cells in numerous publications for the past 5 years. Great consistency!
에서:  Jin | 날짜:  2020-07-21
Works Like Magic
Have been using this cytokine for past 1year and has worked everytime. Very helpful for stimulating and expanding T cell population. Does a great job while performing in-vivo T cell transfer experiments.
에서:  Vineet | 날짜:  2020-08-10
Consistently great cytokine to keep mouse T cells happy
We routinely use this pro-survival homeostasis cytokine to generate mouse memory CD8+ T cells. The pricing and consistency of this cytokine can't be beat, and we have been using it for almost 20 years. All of our cytokines using in our lab are from peprotech.
에서:  Chirag | 날짜:  2020-08-31