All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.
MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), CINC (rat)
APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.
Calculated Molecular Weight:
1mg will be provided as 2x500μg.