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Chemokines

Recombinant Murine LIX (CXCL6) (92 a.a.)

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카다로그 번호 250-17
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Recombinant Murine LIX (CXCL6) (92 a.a.)

CXCL6, also known as LIX in mice, is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX, LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that binds to the CXCR1 and CXCR2 receptors. Recombinant Murine LIX is a 9.8 kDa protein containing 92 amino acid residues.

Source: E.coli

Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2

AA Sequence: APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIQKI LGSDKKKAKR NALAVERTAS VQ

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

Recombinant Murine LIX (CXCL6) (92 a.a.) Biological Activity Graph

Calculated Molecular Weight: 9.8 kDa

Accession Number: P50228

Gene ID: 20311

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Wang, L
주제
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
인용
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 8(19) pge2004673
PubMed ID
제 1 저자
Zhang, H E
주제
Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics.
인용
Molecular & cellular proteomics : MCP; 18(1) pg65-85
PubMed ID
제 1 저자
Yagawa, Y
주제
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
인용
Scientific Reports; 7(1) pg15996
PubMed ID