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Chemokines

Recombinant Murine PF-4 (CXCL4)

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카다로그 번호 250-39
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Recombinant Murine PF-4 (CXCL4)

PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Source: E.coli

Synonyms: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact

AA Sequence: VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.2 kDa

Accession Number: Q9Z126

Gene ID: 56744

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Du, Y
주제
Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.
인용
The Journal of Experimental Medicine; 219(7)
PubMed ID
제 1 저자
Yagawa, Y
주제
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
인용
Scientific Reports; 7(1) pg15996
PubMed ID
제 1 저자
Singh, K
주제
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
인용
Scientific Reports; 7(1) pg4267
PubMed ID