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Growth Factors & Cytokines

Recombinant Rat IL-15

제품 상세

카다로그 번호 400-24
제품 설명

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.  IL-15 exerts its biological activities primarily on T cells.  It is also essential in the development, survival and activation of NK cells.  Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I.  Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.  Recombinant Rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.

Source: E.coli

Synonyms: IL-T

AA Sequence: MNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

Calculated Molecular Weight: 13.5 kDa

Accession Number: P97604

Gene ID: 25670

crossreactivity: Research Interest

Country Of Origin: USA

Not for human use.