New Products

New Products

Our extensive selection of Cytokine, Antibody, ELISA, and Media products is continuously expanding to address your current research interests.

Here you can find a list of our newly released products.

New

Size

95.00 USD 10µg
215.00 USD 50µg
330.00 USD 100µg
577.50 USD 250µg
990.00 USD 500µg
1,650.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Human Apo-SAA1

SKU: AF-300-53

Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of Apo-SAA, normally 1-5 μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apolipoprotein. The human SAA gene codes for a 122 amino acid nonglycosylated polypeptide, which contains an 18 amino acid N-terminal sequence. Recombinant Human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: None

AA Sequence: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

New

Size

95.00 USD 10µg
215.00 USD 50µg
330.00 USD 100µg
577.50 USD 250µg
990.00 USD 500µg
1,650.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Human BMP-13/CDMP-2

SKU: AF-120-04

BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino-acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains. 

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Bone Morphogenetic Protein-13, GDF-6, Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)

AA Sequence (monomer): TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR

Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2.0-3.0 µg/ml.

New

Size

95.00 USD 5µg
215.00 USD 25µg
660.00 USD 100µg
1,155.00 USD 250µg
1,980.00 USD 500µg
3,300.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Human GRO-α/MGSA (CXCL1)

SKU: AF-300-11

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant Human GRO/MGSA is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity, MGSAα, NAP-3, GRO1

AA Sequence: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

Note:

1mg will be provided as 2x500μg.

New

Size

95.00 USD 5µg
215.00 USD 20µg
396.00 USD 50µg
660.00 USD 100µg
1,155.00 USD 250µg
1,980.00 USD 500µg
3,300.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Human I-TAC (CXCL11)

SKU: AF-300-46

I-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, ormonocytes. Recombinant Human I-TAC (CXCL11) is an 8.3 kDa protein containing 73 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. 

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Interferon Inducible T-Cell α Chemokine, B-R1

AA Sequence: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T-cells activated with IL-2.

New

Size

95.00 USD 5µg
215.00 USD 20µg
660.00 USD 100µg
1,155.00 USD 250µg
1,980.00 USD 500µg
3,300.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Human sTNF Receptor Type I

SKU: AF-310-07

TNFRI belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-α or TNF-β to TNFRI initiates a signal transduction pathway that results in the activation of the transduction factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. Soluble TNF Receptor I (sTNFRI) is capable of inhibiting TNF-α and TNF-β activities by acting as a decoy receptor that serves as a sink for the TNF ligands. The human TNFRI gene encodes for a 455 amino acid type I transmembrane protein, which contains a 21 amino acid signal sequence, a 190 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 221 amino acid cytoplasmic domain. Recombinant Human sTNF Receptor Type I is an 18.3 kDa protein (162 amino acid residues) comprising the cysteine-rich, ligand-binding portion of the extracellular domain of the TNFRI protein.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: soluble Tumor Necrosis Factor Type I, TNFRSF1A, TNFAR, p60, p55, CD120a, TNFR1

AA Sequence: MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM GQVEISSCTV DRDTVCGCRK NQYRHYWSEN LFQCFNCSLC LNGTVHLSCQ EKQNTVCTCH AGFFLRENEC VSCSNCKKSL ECTKLCLPQI EN

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its inhibitory effect of the TNF-α mediated cytotoxicity in murine L-929 cells. The  ED50  for this effect in the presence of 0.25 ng/ml of Recombinant Human TNF-α, is 0.05 µg/ml.

New

Size

95.00 USD 5µg
215.00 USD 20µg
660.00 USD 100µg
1,155.00 USD 250µg
1,980.00 USD 500µg
3,300.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Human TECK (CCL25)

SKU: AF-300-45

TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant Human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Thymus Expressed Chemokine

AA Sequence: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSKRNVSLL ISANSGL

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

New

Size

95.00 USD 2µg
215.00 USD 10µg
1,140.00 USD 100µg
1,995.00 USD 250µg
3,420.00 USD 500µg
5,700.00 USD 1mg
Looking for a custom size?
Contact Us

Animal-Free Recombinant Murine IL-21

SKU: AF-210-21

IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include: inducing the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells; the stimulation of IgG production in conjunction with IL-4; and the induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the γ chain (γc) found in other cytokine receptors, including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Interleukin-21, Za11

AA Sequence: MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to stimulate the proliferation of human ANBL-6 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.

New

Size

195.00 USD 50µg
250.00 USD 100µg
1,700.00 USD 1mg
Looking for a custom size?
Contact Us

Anti-Human BAFF (Polyclonal Rabbit)

SKU: 500-P163

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human BAFF. Anti-Human BAFF-specific antibody was purified by affinity chromatography employing an immobilized Human BAFF matrix.

Immunogen: E.coli derived Recombinant Human BAFF (PeproTech catalog# 310-13)

Sandwich ELISA: To detect Human BAFF by sandwich ELISA (using 100μl/well) a concentration of 0.5-2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech’s Biotinylated Anti-Human BAFF (500-P163BT) as a detection antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Human BAFF.

Anti-Human BAFF Sandwich ELISA

Western Blot: To detect Human BAFF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible secondary reagents the detection limit for Recombinant Human BAFF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Anti-Human BAFF Western Blot Unreduced Anti-Human BAFF Western Blot Reduced

Note:

Additional applications tested on a lot‐to‐lot basis. Please contact Technical Support for more information.

New
Catalog Number: 500-P324

Size

195.00 USD 50µg
250.00 USD 100µg
1,700.00 USD 1mg
Looking for a custom size?
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Anti-Human MMP-3

SKU: 500-P324

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-3. Anti-Human MMP-3-specific antibody was purified by affinity chromatography employing an immobilized MMP-3 matrix.

Immunogen: E.coli derived Recombinant Human MMP-3 (PeproTech catalog# 420-03)

Sandwich ELISA: To detect Human MMP-3 by sandwich ELISA (using 100μl/well), a concentration of 0.5-2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech’s Biotinylated Anti-Human MMP-3 (500-P324BT) as a detection antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Human MMP-3.

Anti-Human MMP-3 Sandwich ELISA

Western Blot: To detect Human MMP-3 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human MMP-3 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Anti-Human MMP-3 Western Blot Unreduced Anti-Human MMP-3 Western Blot Reduced

Note:

Additional applications tested on a lot-to-lot basis. Please contact Technical Support for more information.

New
Catalog Number: 500-P267

Size

195.00 USD 50µg
250.00 USD 100µg
1,700.00 USD 1mg
Looking for a custom size?
Contact Us

Anti-Human VEGF-B

SKU: 500-P267

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human VEGF-B. Anti-Human VEGF-B-specific antibody was purified by affinity chromatography employing an immobilized Human VEGF-B matrix.

Immunogen: E.coli derived Recombinant Human VEGF-B (PeproTech catalog# 100-20B)

Sandwich ELISA: To detect Human VEGF-B by sandwich ELISA (using 100μl/well) a concentration of 0.5-2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech’s Biotinylated Anti-Human VEGF-B (500-P267BT) as a detection antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Human VEGF-B.

Anti-Human VEGF-B Sandwich ELISA

Western Blot: To detect Human VEGF-B by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible secondary reagents the detection limit for Recombinant Human VEGF-B is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Anti-Human VEGF-B Western Blot Reduced Anti-Human VEGF-B Western Blot Unreduced

Note:

Additional applications tested on a lot-to-lot basis. Please contact Technical Support for more information.

New
Catalog Number: 500-P308

Size

195.00 USD 50µg
250.00 USD 100µg
1,700.00 USD 1mg
Looking for a custom size?
Contact Us

Anti-Murine LIGHT

SKU: 500-P308

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine LIGHT. Anti-Murine LIGHT-specific antibody was purified by affinity chromatography employing an immobilized Murine LIGHT matrix.

Immunogen: E.coli derived Recombinant Murine LIGHT (PeproTech catalog# 315-12)

Sandwich ELISA: To detect Murine LIGHT by sandwich ELISA (using 100μl/well) a concentration of 0.5-2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech’s Biotinylated Anti-Murine LIGHT (500-P308BT) as a detection antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Murine LIGHT.

Anti-Murine LIGHT Sandwich ELISA

Western Blot: To detect Murine LIGHT by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine LIGHT is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Anti-Murine LIGHT Western Blot Unreduced Anti-Murine LIGHT Western Blot Reduced

Note:

Additional applications tested on a lot-to-lot basis. Please contact Technical Support for more information.

New

Size

195.00 USD 25µg
250.00 USD 50µg
3,400.00 USD 1mg
Looking for a custom size?
Contact Us

Biotinylated Anti-Human BAFF (Polyclonal Rabbit)

SKU: 500-P163BT

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human BAFF. Anti-Human BAFF-specific antibody was purified by affinity chromatography and then biotinylated.

Immunogen: E.coli derived Recombinant Human BAFF (PeproTech catalog# 310-13)

Sandwich ELISA: To detect Human BAFF by sandwich ELISA (using 100μl/well) a concentration of 0.25-1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech’s Polyclonal Anti-Human BAFF (500-P163) as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Human BAFF.

Biotinylated Anti-Human BAFF Sandwich ELISA

Western Blot: To detect Human BAFF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible development reagents the detection limit for Recombinant Human BAFF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Biotinylated Anti-Human BAFF Western Blot Unreduced Biotinylated Anti-Human BAFF Western Blot Reduced

Note:

1mg will be provided as 2x500μg.

New

Size

195.00 USD 25µg
250.00 USD 50µg
3,400.00 USD 1mg
Looking for a custom size?
Contact Us

Biotinylated Anti-Human MMP-3

SKU: 500-P324BT

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MMP-3. Anti-Human MMP-3-specific antibody was purified by affinity chromatography and then biotinylated.

Immunogen: E.coli derived Recombinant Human MMP-3 (PeproTech catalog# 420-03)

Sandwich ELISA: To detect Human MMP-3 by sandwich ELISA (using 100μl/well), a concentration of 0.25-1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech’s Polyclonal Anti-Human MMP-3 (500-P324) as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Human MMP-3.

Biotinylated Anti-Human MMP-3 Sandwich ELISA

Western Blot: To detect Human MMP-3 by Western Blot analysis, this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible development reagents, the detection limit for Recombinant Human MMP-3 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Biotinylated Anti-Human MMP-3 Western Blot Reduced Biotinylated Anti-Human MMP-3 Western Blot Unreduced

Note:

1mg will be provided as 2x500μg.

New

Size

195.00 USD 25µg
250.00 USD 50µg
3,400.00 USD 1mg
Looking for a custom size?
Contact Us

Biotinylated Anti-Human Resistin (Polyclonal Rabbit)

SKU: 500-P183BT

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits pre-immunized with highly pure Recombinant Human Resistin. Anti-Human Resistin specific antibody was purified by affinity chromatography and then biotinylated.

Immunogen: E.coli derived Recombinant Human Resistin (PeproTech catalog# 450-19)

Sandwich ELISA: To detect Human Resistin by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.25 – 1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech’s Polyclonal Anti-Human Resistin (500-P183) as a capture antibody, allows the detection of at least 0.2 – 0.4 ng/well of Recombinant Human Resistin.

Biotinylated Anti-Human Resistin (Polyclonal Rabbit) Sandwich ELISA

Western Blot: To detect Human Resistin Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Resistin is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Biotinylated Anti-Human Resistin (Polyclonal Rabbit) Western Blot Reduced Biotinylated Anti-Human Resistin (Polyclonal Rabbit) Western Blot Unreduced

Note:

1mg will be provided as 2x500μg.

New

Size

195.00 USD 25µg
250.00 USD 50µg
3,400.00 USD 1mg
Looking for a custom size?
Contact Us

Biotinylated Anti-Human VEGF-B

SKU: 500-P267BT

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human VEGF-B. Anti-Human VEGF-B-specific antibody was purified by affinity chromatography and then biotinylated.

Immunogen: E.coli derived Recombinant Human VEGF-B (PeproTech catalog# 100-20B)

Sandwich ELISA: To detect Human VEGF-B by sandwich ELISA (using 100μl/well) a concentration of 0.25-1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech’s Polyclonal Anti-Human VEGF-B (500-P267) as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Human VEGF-B.

 Biotinylated Anti-Human VEGF-B Sandwich ELISA

Western Blot: To detect Human VEGF-B by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible development reagents the detection limit for Recombinant Human VEGF-B is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

 Biotinylated Anti-Human VEGF-B Western Blot Reduced  Biotinylated Anti-Human VEGF-B Western Blot Unreduced

Note:

1mg will be provided as 2x500μg.

New

Size

195.00 USD 25µg
250.00 USD 50µg
3,400.00 USD 1mg
Looking for a custom size?
Contact Us

Biotinylated Anti-Murine LIGHT

SKU: 500-P308BT

Source: Polyclonal Rabbit

Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine LIGHT. Anti-Murine LIGHT-specific antibody was purified by affinity chromatography and then biotinylated.

Immunogen: E.coli-derived Recombinant Murine LIGHT (PeproTech catalog# 315-12)

Sandwich ELISA: To detect Murine LIGHT by sandwich ELISA (using 100μl/well) a concentration of 0.25-1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech’s Polyclonal Anti-Murine LIGHT (500-P308) as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant Murine LIGHT.

Biotinylated Anti-Murine LIGHT Sandwich ELISA

Western Blot: To detect Murine LIGHT by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/ml. When used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine LIGHT is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Biotinylated Anti-Murine LIGHT Western Blot Unreduced Biotinylated Anti-Murine LIGHT Western Blot Reduced

Note:

1mg will be provided as 2x500μg.

New

Size

100.00 USD 1kit
Looking for a custom size?
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Human IL-13 Mini ABTS ELISA Development Kit

SKU: 900-M23

Human IL-13 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant Human IL-13 in a sandwich ELISA format. Using the ELISA protocol, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay Human IL-13 in approximately 200 ELISA plate wells.

New

Size

275.00 USD 500mL
Looking for a custom size?
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PeproGrow™ hMSC Mesenchymal Stem Cell Media

SKU: XF-HMSC-500

PeproGrow hMSC (Mesenchymal Stem Cell) Medium is a xeno-free, human serum containing, phenol red-free complete media formulation originally designed for thein vitro expansion of adipose-derived human mesenchymal stem cells (ADMSCs) while maintaining full multipotency. Since its design, this media formulation has been shown to be suitable for the sustained growth of adipose tissue-derived, bone marrow-derived, umbilical cord-derived, placental-derived, and urine-derived MSCs in both adherent and suspension culture. For optimal results, culturing should be conducted on a surface coated with PeproTech’s Animal-Free Human Vitronectin Matrix as a surface-coating reagent; however, other suitable extracellular matrix (ECM) proteins, such as fibronectin or vitronectin, can be used. PeproGrow hMSC Medium was designed and developed in collaboration with American CryoStem Corporation, and is supplied as a 500mL bottle of PeproGrow hMSC Basal Medium containing a human serum component, and a separate, lyophilized vial of animal-free PeproGrow hMSC Growth Factor Supplement. The addition of the separate, lyophilized growth factor supplement to the basal medium results in a complete medium containing all growth factors and supplements necessary for optimal expansion of human mesenchymal stem cells in culture. Additional companion products, including PeproTech’s Animal-Free Vitronectin Matrix and Buffer Kit, are available separately.

MSC growth curve

 

New

Size

80.00 USD 2µg
195.00 USD 10µg
1,040.00 USD 100µg
1,820.00 USD 250µg
3,120.00 USD 500µg
5,200.00 USD 1mg
Looking for a custom size?
Contact Us

Recombinant Human IL-36α (IL-1F6)

SKU: 200-36A

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8), and γ (IL-1F9). IL-36α is highly expressed in psoriatic plaques, as are IL-36β and IL-36γ, and is the only IL-1 family member found to be expressed by T-cells, as well as monocytes and B-cells. Primarily found in skin and lymphoid tissues, IL-36α is also found to a lesser extent in tissues of the fetal brain, trachea, stomach, and intestine. IL-36α signals through a combination of the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells, and the widely expressed IL-RAcP (IL-1 receptor accessory protein). IL-36α also functions as an agonist of NF-kappaB and MAPK pathways, and induces the production of proinflammatory cytokines and chemokines, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36α is a 17.2 kDa protein containing 154 amino acid residues.

Source: E.coli

Synonyms: Interleukin-36α, IL36A, Interleukin-1 family member 6 (IL-1F6), FIL1ε (FIL1E), Interleukin-1ε (IL1E)

AA Sequence: MKIDTPQQGS IQDINHRVWV LQDQTLIAVP RKDRMSPVTI ALISCRHVET LEKDRGNPIY LGLNGLNLCL MCAKVGDQPT LQLKEKDIMD LYNQPEPVKS FLFYHSQSGR NSTFESVAFP GWFIAVSSEG GCPLILTQEL GKANTTDFGL TMLF

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Measured by its ability to inhibit secretion of IL-8 by A431 cells in the prescence of IL-36γ.

New

Size

80.00 USD 5µg
195.00 USD 20µg
780.00 USD 100µg
1,365.00 USD 250µg
2,340.00 USD 500µg
3,900.00 USD 1mg
Looking for a custom size?
Contact Us

Recombinant Human Sclerostin

SKU: 100-49

Sclerostin, a glycoprotein predominantly secreted by osteocytes, is a member of the Cerberus/DAN family of putative BMP antagonists that functions as an endogenous regulator of the canonical Wnt signaling pathway and an inhibitory regulator of bone homeostasis. Although expressed nearly exclusively by osteocytes, sclerostin can also be found at significant levels elsewhere, such as bone, bone marrow, cartilage, the kidney, and the liver, and has also been shown to be produced by hypertrophic chondrocytes and cementocytes. Like DKK family members DKK-1 and DKK-4, sclerostin plays an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL Receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. Sclerostin has also been shown to interact directly with LRP4 via its extracellular domain to facilitate inhibition of Wnt signaling, and can catabolically promote osteoclast activity by increasing osteocyte expression of RANKL. Sclerostin’s critical involvement in the regulation of bone formation and resorption is emphasized by two bone dysplasia disorders, sclerosteosis and van Buchem disease (VBD), caused by rare autosomal recessive mutations that result in progressive bone overgrowth and hypermineralization due to markedly decreased sclerostin levels. PeproTech's CHO cell-derived Recombinant Human Sclerostin is a 186-amino-acid-length glycoprotein with a calculated molecular weight of 21.0 kDa. As a result of glycosylation, Recombinant Human Sclerostin migrates with an apparent molecular mass of approximately 26-32 kDa by SDS-PAGE gel, under non-reducing conditions.

Source: CHO cells

Synonyms: SOST, SOST1, CDD, VBCH, DAND6

AA Sequence: AFKNDATEII PELGEYPEPP PELENNKTMN RAENGGRPPH HPFETKDVSE YSCRELHFTR YVTDGPCRSA KPVTELVCSG QCGPARLLPN AIGRGKWWRP SGPDFRCIPD RYRAQRVQLL CPGGEAPRAR KVRLVASCKC KRLTRFHNQS ELKDFGTEAA RPQKGRKPRP RARSAKANQA ELENAY

Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to downregulate alkaline phosphatase activity in differentiating MC3T3‑E1 cells in the presence of 20ng/ml murine Wnt‑3a.

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