Growth Factors & Cytokines

Recombinant Human FGF-4

Product Details

Catalog Number: 100-31
Description:

FGF-4 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-4, HST-1, Transforming protein KS3, HBGF-4

AA Sequence: GRGGAAAPT APNGTLEAEL ERRWESLVAL SLARLPVAAQ PKEAAVQSGA GDYLLGIKRL RRLYCNVGIG FHLQALPDGR IGGAHADTRD SLLELSPVER GVVSIFGVAS RFFVAMSSKG KLYGSPFFTD ECTFKEILLP NNYNAYESYK YPGMFIALSK NGKTKKGNRV SPTMKVTHFL PRL

Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

Note:

1mg will be provided as 2x500μg.

Cross Reactivity:
Chicken, Human, Mouse, N/A, Pig, Rat
Research Interest

Country Of Origin: USA

Research Use Only: Not for use in diagnostic or therapeutic procedures.