Recombinant Human GRO-α/MGSA (CXCL1) 0 ReviewsSubmit a Review Product Details Catalog Number: 300-11 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant Human GRO-α/MGSA is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity, MGSAα, NAP-3, GRO1 AA Sequence: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P09341 Gene ID: 2919 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Bacteria, Hamster, Human, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing Recent Citations First Author Bouhaddou, M Title The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Citation Cell; 182(3) pg685-712.e19 PubMed ID 32645325 First Author Yang, I Title Oxidative stress enhanced the transforming growth factor-β2-induced epithelial-mesenchymal transition through chemokine ligand 1 on ARPE-19 cell. Citation Scientific Reports; 10(1) pg4000 PubMed ID 32132577 First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed ID 31167786
