Recombinant Human HPRG 0 ReviewsSubmit a Review Product Details Catalog Number: 100-60 Description: Histidine-proline-rich glycoprotein (HPRG), a member of the Cystatin structural superfamily, is an abundantly secreted multi-domain glycoprotein. Although the physiological function is largely unknown, HPRG potentially regulates physiological processes such as cell adhesion and migration, fibrinolysis, coagulation, complement activation, immune complex clearance and phagocytosis of apoptotic cells. HPRG can exert anti-angiogneic activity by stimulating apoptosis of endothelial cells. Recombinant Human HPRG is a 57.7 kDa glycoprotein containing 507 amino acid residues. Source: CHO cells Synonyms: Histidine-Proline-Rich Glycoprotein, Histidine-rich glycoprotein (HRG), HRGP, THPH11 AA Sequence: VSPTDCSAVE PEAEKALDLI NKRRRDGYLF QLLRIADAHL DRVENTTVYY LVLDVQESDC SVLSRKYWND CEPPDSRRPS EIVIGQCKVI ATRHSHESQD LRVIDFNCTT SSVSSALANT KDSPVLIDFF EDTERYRKQA NKALEKYKEE NDDFASFRVD RIERVARVRG GEGTGYFVDF SVRNCPRHHF PRHPNVFGFC RADLFYDVEA LDLESPKNLV INCEVFDPQE HENINGVPPH LGHPFHWGGH ERSSTTKPPF KPHGSRDHHH PHKPHEHGPP PPPDERDHSH GPPLPQGPPP LLPMSCSSCQ HATFGTNGAQ RHSHNNNSSD LHPHKHHSHE QHPHGHHPHA HHPHEHDTHR QHPHGHHPHG HHPHGHHPHG HHPHGHHPHC HDFQDYGPCD PPPHNQGHCC HGHGPPPGHL RRRGPGKGPR PFHCRQIGSV YRLPPLRKGE VLPLPEANFP SFPLPHHKHP LKPDNQPFPQ SVSESCPGKF KSGFPQVSMF FTHTFPK Purity: ≥ 90% by SDS-PAGE gel and HPLC analyses. Biological Activity: Measured by its ability to support adhesion of Con-A activated MOLT-4 cells to the Recombinant Human HPRG-coated surface. The ED50 for this effect is 1.5-2.0 μg/ml. Calculated Molecular Weight: 57.7 kDa Accession Number: P04196 Gene ID: 3273 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Apoptosis Cancer Chemotaxis Immune System Proliferation
