Neurotrophins

Recombinant Human/Rat Neuritin

Product Details

Catalog Number: 450-36D
Description:

Neuritin is a neurotrophic factor that is expressed in response to the induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system, and in neuronal structures related to synaptic plasticity in the adult nervous system.   Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.   Recombinant Human/Rat Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.

Source: E.coli

Synonyms: CPG15, NRN1

AA Sequence (monomer): AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml.

Cross Reactivity:
Rat
Research Interest

Country Of Origin: USA

Research Use Only: Not for use in diagnostic or therapeutic procedures.