Animal-Free Cytokines

Animal-Free Recombinant Murine FGF-basic

Product Details

Catalog Number: AF-450-33
Description:

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells.  FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.  Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

AA Sequence: PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS

Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells.  The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.

Cross Reactivity:
Mouse
Research Interest

Country Of Origin: USA

Research Use Only: Not for use in diagnostic or therapeutic procedures.