Recombinant Murine MEC (CCL28) 0 ReviewsSubmit a Review Product Details Catalog Number: 250-30 Description: MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8 T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Murine MEC is a 12.6 kDa protein containing 111 amino acid residues. Source: E.coli Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1 AA Sequence: SEAILPMASS CCTEVSHHVS GRLLERVSSC SIQRADGDCD LAAVILHVKR RRICISPHNR TLKQWMRASE VKKNGRENVC SGKKQPSRKD RKGHTTRKHR TRGTHRHEAS R Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine lymphocytes using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 12.6 kDa Accession Number: Q9JIL2 Gene ID: 56838 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Cross Reactivity Cited in References: Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing Recent Citations First Author Yagawa, Y Title Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Citation Scientific Reports; 7(1) pg15996 PubMed ID 29167448 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed ID 28655871 First Author Bahar, M W Title Structure and function of A41, a vaccinia virus chemokine binding protein. Citation PLoS Pathogens; 4(1) pge5 PubMed ID 18208323
