Prolactin is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoregulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant Murine Prolactin is a 22.5 kDa globular protein containing 198 amino acid residues.
Mammotropin, Luterotropic hormone, Lutetropin
MLPICSAGDC QTSLRELFDR VVILSHYIHT LYTDMFIEFD KQYVQDREFM VKVINDCPTS SLATPEDKEQ ALKVPPEVLL NLILSLVQSS SDPLFQLITG VGGIQEAPEY ILSRAKEIEE QNKQLLEGVE KIISQAYPEA KGNGIYFVWS QLPSLQGVDE ESKILSLRNT IRCLRRDSHK VDNFLKVLRC QIAHQNNC
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.